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Stage 2 Colon Cancer Drugs

Stopping the spread of stage 2 colon cancer

You have Stage 2 colon cancer. What does this mean? Usually Stage 2 cancer is operable, and you may or may not need chemotherapy. There is a 60% to 75% cure rate with surgery alone. Your cancer doctor can tell you whether or not chemotherapy (use of anticancer drugs) is appropriate for you).

If your cancer has spread outside of the colon, then you might be a candidate for chemotherapy. There are drugs to battle stage 2 cancer that could add months or years to your life. Doctors prescribe these anticancer drugs either separately or in combinations.

The drug treatments and side effects may be rough to take, but it is a battle to get rid of the cancer or slow it down. Your cancer doctor has knowledge of the latest aggressive drug treatments and their side effects. Here is an introduction to this topic.

A traditional treatment is:

  • Eloxatin® (oxaliplatin) combined with
  • Adrucil® (5-fluorouracil) and Wellcovorin® leucovorin

FDA approved this combination treatment for patients to use after surgical removal of the cancer. Eloxatin® contains a platinum metal complex that kills cancer cells. Adrucil® slows down and stops growth of cancer cells. Wellcovorin® is a vitamin complex that contains folic acid.

There may be unwanted side effects with anticancer drugs. Therefore, you must discuss the possible side effects of anticancer drugs with your doctor before taking these medicines.

Combinations of anticancer drugs such as:

  • Xeloda® (capecitabine), which is administered orally and shrinks tumors,
  • Camptosar® (irinotecan), which kills cancer cells, and
  • Eloxatin® (oxaliplatin), which also kills cancers cells, have been linked to increased survival rates for colon cancer.

Therapy Medicines:

Targeted therapy as the name implies is accomplished with chemicals that attack cancer cell growth and/or survival. The following drugs are targeted therapy medicines:

  • Erbitux® (cetuximab) shows promise for extending survival time in patients with advanced colorectal cancer. Erbitux interferes with growth of cancer cells by binding with epidermal growth factor receptors (EGFR) on cancer cells. The most common side effects of Erbitux are: acne-like rash, tiredness, diarrhea, nausea, vomiting, fever, and constipation.
  • Vectibix® (panitumumab) works in a similar fashion to Erbitux® by targeting EGFR on cancer cells.
  • Avastin® (bevacizumab) interferes with growth of cancer cells by preventing or slowing the growth of new blood vessels (angiogenesis). Avastin starves the cancer cells of nutrients.

Benefits

These medications are examples of anticancer drugs that can add months, maybe years to your life. This is called having a positive effect on survival time. Speak with your doctor about the medication options for stage 2 colon cancer. There may even be a genetic test that can tell how well your type of cancer will respond to chemotherapy.

Your doctor can explain recent clinical studies and the associated colon cancer survival statistics. You may even be able to participate in a clinical study of a new anticancer drug! Don't wait. Stop stage 2 colon cancer before it becomes stage 3 cancer.

Written by Steve Northcott - 2/24/09

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