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CCR News, Issue #039 -- Why Treatment with 5FU Sometimes Fails July 20, 2010 |
Christine Traxler, MD, Editor
COLON CANCER SCREENING VITALIn the upcoming year, about 51,000 individuals will die from colon cancer and most of these will die because they failed to follow American Cancer Society screening methods for colon cancer. Those recommendations, including having a first colonoscopy around age 50, will mean that fewer people will die from colon cancer. Currently there are few new and great treatments out there for colon cancer. This leaves adequate prevention and early diagnosis the best option.
NINE YEAR OLD GIRL RAISES $40,000 FOR COLON CANCERA nine year old who lost her maternal grandfather to colon cancer wanted to do something so no kid will have to go without their grandfather. She’s been raising money for the last six years and has been the top winning fundraiser for Relay for Life for most of those six years. Brannon Russell has been speaking to the public about colon cancer and raising funds for cancer research even at a young age. She takes her purple pig and a Radio Flyer wagon and has no problems raising thousands of dollars for cancer research. She began raising funds for colon cancer before she even understood exactly what that meant.
AFFORDABLE CANCER PREVENTION AND SCREENING IN THE WORKSCurrently, the Obama White House is discussing what the government can do about preventative care. This begins the Affordable Care Act that will give millions of Americans access to preventative care by making preventative care free, even to those that don’t have insurance. They note that up to 59 million adults and 11 million children have insurance but no coverage for immunizations. Many mothers, especially African Americans, do not get prenatal care. Colon cancer screening is only at a rate of 37 percent among Latinos, far less than in Caucasians. New programming will make screening tests free to those who do not have adequate coverage for screening.
COLON CANCER PATIENTS: NEW CASES DROPPINGExperts are predicting that 4400 fewer US residents will have a diagnosis of colon or rectal cancer compared to last year. The death rate from cancer, however, up to 51,000, is expected to remain the same. African Americans will continue to get more colon cancer than Caucasians. In addition, their survival rate is also expected to decrease. Colon cancer will still be the third most commonly diagnosed cancer in both men and women, with 142,000 cases of cancer of the colon or rectum diagnosed each year.
WHY TREATMENT WITH 5FU SOMETIMES FAILSSome colon cancer patients actually have worse outcomes with 5FU than they do without getting the treatment. This is due to a condition called defective mismatch repair or dMMR. It affects about 15 percent of colon cancer patient. It is becoming increasingly obvious that the doctor needs to find out about the mismatch repair status of the cancer patient before giving them 5FU for their cancer. Knowing the mismatch repair status of colon cancer patients can make all the difference in what is given to cancer patients as treatment for their disease.
RISK FACTORS FOR COLON AND RECTAL CANCERColon cancer involves cancer of the large intestine, while rectal cancer is cancer of the last six inches of the colon. They are together referred to as colorectal cancer. Together, they are diagnosed at a rate of about 151,000 per year. Risk factors for colon cancer include age greater than 50, history of colon polyps or previous colon cancer, having ulcerative colitis or Crohn’s disease or having certain genetic reasons for having multiple polyps of the colon.
The faces of colon cancer are looking younger and younger. The United States Preventative Services Task Force and the American Cancer Society recommend colon cancer screening at the age of 50. Yet, dying of colon cancer at the age of 40 is no longer an exception nor is it a rare phenomenon. There is an increasingly compelling evidence that the incidence of colon cancer among people in their thirties and forties is rising at an alarming rate. Please join me on my quest to get the American Cancer Society and the United States Preventative Task Force to review and change their colon cancer screening guidelines to start colon cancer screening at age 40 for the general population and at 35 for people who have compelling risk factors such as a family history of colon cancer.Effective cancer treatment is nowhere in the horizon, so early detection is the key to survival. One more life needlessly lost to colon cancer is one life too many. The purpose of changing the guidelines as mentioned above is to pave the road to get insurance companies to pay for screening colonoscopies at the ages of 35 and 40. Please sign the petition make sure to forward it to your friends.Your collaboration is greatly appreciated. The Quest to Change the Colon Cance Screening Check out the eBook Store! We've written several e-books in plain english that you may find helpful in your battle against cancer.
DO YOU HAVE A PERSONAL STORY ABOUT COLON CANCER?It is our heartfelt desire that you become a part of the Colon Cancer Resource website and contribute your personal experience and stories regarding colon cancer so that others may benefit. Your story may help inspire someone in their fight against colon cancer. Your tips, experiences and advice are all welcome and will be published here. You can remain anonymous if you choose. It's easy to contribute. After you post your story, other visitors can comment and contribute to your story and if you choose, you will be notified by email when this happens. You can submit your own story and read about other peoples experience by selecting one of the following links:
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